Those of us who shoot 6.5 Creedmoor guns — and there are a lot of us — have been shooting them through .30 caliber suppressors. That’s been the can that makes the most sense. Depending on what you own, you could even be using a .36 or a .46 caliber can. The bigger the bore, the more calibers you can shoot, but the less effective the suppressor is in reducing noise.